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Article

Vector Integration Sites Identification for Gene-Trap Screening in Mammalian Haploid Cells.

Scientific reports - 17 Mar 2017

Yu Jian, Ciaudo Constance

Abstract excerpt

Forward genetic screens using retroviral (or transposon) gene-trap vectors in a haploid genome revolutionized the investigation of molecular networks in mammals. However, the sequencing data generated by Phenotypic interrogation followed by Tag sequencing (PhiT-seq) were not well characterized. The analysis of human and mouse haploid screens allowed us to describe PhiT-seq data and to define quality control...

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Identifiers

PMID: 28303933
DOI: 10.1038/srep44736
PMCID: PMC5356192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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