Article
Mutational Profile from Targeted NGS Predicts Survival in LDCT Screening-Detected Lung Cancers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jun 2017
Verri Carla, Borzi Cristina, Holscher Todd, Dugo Matteo, Devecchi Andrea, Drake Katherine, Sestini Stefano, Suatoni Paola, Romeo Elisa, Sozzi Gabriella, Pastorino Ugo, Boeri Mattia
Abstract excerpt
BACKGROUND: The issue of overdiagnosis in low-dose computed tomography (LDCT) screening trials could be addressed by the development of complementary biomarkers able to improve detection of aggressive disease. The mutation profile of LDCT screening-detected lung tumors is currently unknown. METHODS: Targeted next-generation sequencing was performed on 94 LDCT screening-detected lung tumors. Associations with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
