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Article

Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.

Neurology - 11 Apr 2017

Gramatzki Dorothee, Kickingereder Philipp, Hentschel Bettina, Felsberg Jörg, Herrlinger Ulrich, Schackert Gabriele, Tonn Jörg-Christian, Westphal Manfred, Sabel Michael, Schlegel Uwe, Wick Wolfgang, Pietsch Torsten, Reifenberger Guido, Loeffler Markus, Bendszus Martin, Weller Michael

Abstract excerpt

OBJECTIVE: To explore an association with survival of modifying the current standard of care for patients with newly diagnosed glioblastoma of surgery followed by radiotherapy plus concurrent and 6 cycles of maintenance temozolomide chemotherapy (TMZ/RT → TMZ) by extending TMZ beyond 6 cycles. METHODS: The German Glioma Network cohort was screened for patients with newly diagnosed glioblastoma who received TMZ/RT...

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Source

Identifiers

PMID: 28298550
DOI: 10.1212/WNL.0000000000003809

Genes

MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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