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Article

Variability in statin-induced changes in gene expression profiles of pancreatic cancer

9 Mar 2017

Abstract excerpt

Statins, besides being powerful cholesterol-lowering drugs, also exert potent anti-proliferative activities. However, their anti-cancer efficacy differs among the individual statins. Thus, the aim of this study was to identify the biological pathways affected by individual statins in an in vitro model of human pancreatic cancer. The study was performed on a human pancreatic cancer cell line MiaPaCa-2, exposed to...

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PMID: 28276528
DOI: 10.1038/srep44219

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