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Article

Global Transcriptional Changes Following Statin Treatment in Breast Cancer

3 Apr 2015

Abstract excerpt

BACKGROUND: Statins purportedly exert antitumoral effects, but the underlying mechanisms are currently not fully elucidated. The aim of this study was to explore potential statin-induced effects on global gene expression profiles in primary breast cancer. EXPERIMENTAL DESIGN: This window-of-opportunity phase II trial enrolled 50 newly diagnosed breast cancer patients prescribed atorvastatin (80 mg/day) for 2...

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PMID: 25840970
DOI: 10.1158/1078-0432.ccr-14-1403

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