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Article

Influence of Treg cells and HBV genotype on sustained response and drug resistance in the treatment with nucleoside drugs.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 2 Mar 2017

Zhang Y R, Li B, Wang C X, Zhou N, Qi W, Li X L, Wu L Y, Wei S F, Zhang Y D

Abstract excerpt

We aimed to investigate the influence of regulatory T cells including CD4+CD25+, CD8+CD28- and hepatitis B virus (HBV) genotype on sustained virological response and tolerance of nucleoside drugs. One hundred and thirty-seven patients were enrolled. Lamivudine was administered to 84 patients. Entecavir was administered to the other 53 patients. Before treatment, biochemical tests, HBV DNA load, HBV serum level,...

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Identifiers

PMID: 28273209
DOI: 10.1590/1414-431X20165796
PMCID: PMC5378451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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