Population differences in associations of serotonin transporter promoter polymorphism (5HTTLPR) di- and triallelic genotypes with blood pressure and hypertension prevalence.

doi:10.1016/j.ahj.2016.12.013

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Article

Population differences in associations of serotonin transporter promoter polymorphism (5HTTLPR) di- and triallelic genotypes with blood pressure and hypertension prevalence.

American heart journal - 1 Mar 2017

Williams Redford B, Bishop George D, Haberstick Brett C, Smolen Andrew, Brummett Beverly H, Siegler Ilene C, Babyak Michael A, Zhang Xiaodong, Tai E Shyong, Lee Jeannette Jen-Mai, Tan Maudrene, Teo Yik Ying, Cai Shiwei, Chan Edmund, Halpern Carolyn Tucker, Whitsel Eric A, Bauldry Shawn, Harris Kathleen Mullan

Abstract excerpt

Based on prior research finding the 5HTTLPR L allele associated with increased cardiovascular reactivity to laboratory stressors and increased risk of myocardial infarction, we hypothesized that the 5HTTLPR L allele will be associated with increased blood pressure (BP) and increased hypertension prevalence in 2 large nationally representative samples in the United States and Singapore. METHODS: Logistic...

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PMID: 28267464
DOI: 10.1016/j.ahj.2016.12.013
PMCID: PMC5473420

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