Article
Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms with Hepatocellular Carcinoma in Taiwan.
International journal of medical sciences - 1 Jan 2017
Huang Wayne Shih-Wei, Lin Hung-Yu, Yeh Chao-Bin, Chen Li-You, Chou Ying-Erh, Yang Shun-Fa, Liu Yu-Fan
Abstract excerpt
Hepatocellular carcinoma (HCC) is the second leading cause of cancer death in Taiwan. Multiple risk factors, such as chronic hepatitis B or C virus infection, carcinogen exposure, cirrhosis, and various single-nucleotide polymorphisms (SNPs), are considered to contribute to hepatocarcinogenesis. Chitinase-3-like protein 1 (CHI3L1), a biomarker implicated in inflammation and tissue remodeling, plays a promoting...
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