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Article

Individualized Breast Cancer Characterization through Single-Cell Analysis of Tumor and Adjacent Normal Cells.

Cancer research - 15 May 2017

Anjanappa Manjushree, Cardoso Angelo, Cheng Lijun, Mohamad Safa, Gunawan Andrea, Rice Susan, Dong Yan, Li Lang, Sandusky George E, Srour Edward F, Nakshatri Harikrishna

Abstract excerpt

There is a need to individualize assays for tumor molecular phenotyping, given variations in the differentiation status of tumor and normal tissues in different patients. To address this, we performed single-cell genomics of breast tumors and adjacent normal cells propagated for a short duration under growth conditions that enable epithelial reprogramming. Cells analyzed were either unselected for a specific...

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Identifiers

PMID: 28249895
DOI: 10.1158/0008-5472.CAN-16-3308
PMCID: PMC5441682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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