Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome

21 Oct 2016

Abstract excerpt

CD8+ alpha beta T cells, marked predominance of HvG clones, and accelerated T cell turnover in the graft. Ultimately, these recipient T cells acquired a steady state tissue-resident phenotype, but regained CD28 expression during rejections. Increased ratios of GvH to HvG clones were seen in non-rejectors, potentially mitigating the constant threat of rejection posed by HvG clones persisting within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Renal Transplantation Outcomes and Treatments
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28239678
DOI: 10.1126/sciimmunol.aah3732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcomePMID 28239678Read ↗

Plasticity of intragraft alloreactive T cell clones in human gut correlates with transplant outcomesSemantic proximity Read ↗

Dynamic establishment and maintenance of the human intestinal B cell population and repertoire following transplantationSemantic proximity Read ↗

Donor lymphoid organs are a major site of alloreactive T-cell priming following intestinal transplantation.Semantic proximity Read ↗

Understanding the alloresponse: New approaches to graft-versus-host disease preventionSemantic proximity Read ↗

The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host diseaseSemantic proximity Read ↗

Regulating the Immune Response to TransplantsSemantic proximity Read ↗

Identification of a Highly Functional Effector CD8 <sup>+</sup> T Cell Program after Transplantation in Mice and HumansSemantic proximity Read ↗

Host-reactive CD8+ memory stem cells in graft-versus-host diseaseSemantic proximity Read ↗

Donor regulatory T cells rapidly adapt to recipient tissues to control murine acute graft-versus-host diseaseSemantic proximity Read ↗

Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primatesSemantic proximity Read ↗

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic TransplantationSemantic proximity Read ↗

A Unique Subset of Self-specific Intraintestinal T Cells Maintains Gut IntegritySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.