Article
Liquid biopsies come of age: towards implementation of circulating tumour DNA.
Nature reviews. Cancer - 1 Apr 2017
Wan Jonathan C M, Massie Charles, Garcia-Corbacho Javier, Mouliere Florent, Brenton James D, Caldas Carlos, Pacey Simon, Baird Richard, Rosenfeld Nitzan
Abstract excerpt
Improvements in genomic and molecular methods are expanding the range of potential applications for circulating tumour DNA (ctDNA), both in a research setting and as a 'liquid biopsy' for cancer management. Proof-of-principle studies have demonstrated the translational potential of ctDNA for prognostication, molecular profiling and monitoring. The field is now in an exciting transitional period in which ctDNA...
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