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Article

Phenome-wide association studies: a new method for functional genomics in humans.

The Journal of physiology - 15 Jun 2017

Roden Dan M

Abstract excerpt

In experimental physiological research, a common study design for examining the functional role of a gene or a genetic variant is to introduce that genetic variant into a model organism (such as yeast or mouse) and then to search for phenotypic consequences. The development of DNA biobanks linked to dense phenotypic information enables such an experiment to be applied to human subjects in the form of a...

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PMID: 28229460
DOI: 10.1113/JP273122
PMCID: PMC5471509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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