Article
The ADAMTS9 gene is associated with cognitive aging in the elderly in a Taiwanese population.
PloS one - 1 Jan 2017
Lin Eugene, Tsai Shih-Jen, Kuo Po-Hsiu, Liu Yu-Li, Yang Albert C, Kao Chung-Feng, Yang Cheng-Hung
Abstract excerpt
Evidence indicates that the pathophysiologic mechanisms associated with insulin resistance may contribute to cognitive aging and Alzheimer's diseases. In this study, we hypothesize that single nucleotide polymorphisms (SNPs) within insulin resistance-associated genes, such as the ADAM metallopeptidase with thrombospondin type 1 motif 9 (ADAMTS9), glucokinase regulator (GCKR), and peroxisome proliferator activated...
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