Article
Dynamic tracing for epidermal growth factor receptor mutations in urinary circulating DNA in gastric cancer patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2017
Shi Xiu-Qin, Xue Wen-Hua, Zhao Song-Feng, Zhang Xiao-Jian, Sun Wukong
Abstract excerpt
The mutations of epidermal growth factor receptor are detected in gastric cancer, indicating its suitability as a target for receptor tyrosine kinase inhibitors, as well as a marker for clinical outcome of chemotherapeutic treatments. However, extraction of quality tumor tissue for molecular processes remains challenging. Here, we aimed to examine the clinical relevance of urinary cell-free DNA as an alternative...
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