Article
Comparative analysis of PD-L1 expression between primary and metastatic pulmonary adenocarcinomas.
European journal of cancer (Oxford, England : 1990) - 1 Apr 2017
Kim Sehui, Koh Jaemoon, Kwon Dohee, Keam Bhumsuk, Go Heounjeong, Kim Young A, Jeon Yoon Kyung, Chung Doo Hyun
Abstract excerpt
Programmed death-ligand 1 (PD-L1) expression in pulmonary adenocarcinomas (pADCs) was implicated in predicting anti-PD-1/PD-L1 therapy efficacy. However, the differential expression of PD-L1 between primary and metastatic pADC remains unclear. Thus, we addressed this issue. In total, 161 paired primary and metastatic tumour tissues from 146 patients with pADC were collected. Most of the cases had regional nodal...
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