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Article

Discordance of immunotherapy response predictive biomarkers between primary lesions and paired metastases in tumours: A systematic review and meta-analysis.

EBioMedicine - 1 Jan 2021

Zou Yutian, Hu Xiaoqian, Zheng Shaoquan, Yang Anli, Li Xing, Tang Hailin, Kong Yanan, Xie Xiaoming

Abstract excerpt

BACKGROUND: Several biomarkers predict the efficacy of immunotherapy, which is essential for selecting patients who would potentially benefit. Discordant status of these biomarkers between primary tumours and paired metastases has been increasingly revealed. We aimed to comprehensively summarize the incidence of this phenomenon. METHODS: Databases were searched to identify studies reporting primary-to-metastatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33310681
DOI: 10.1016/j.ebiom.2020.103137
PMCID: PMC7736926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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