Article
Protector effect of α-thalassaemia on cholecystitis and cholecystectomy in sickle cell disease.
Hematology (Amsterdam, Netherlands) - 1 Aug 2017
Pontes Robéria M, Costa Elaine S, Siqueira Patrícia F R, Medeiros Jussara F F, Soares Andréa, de Mello Fabiana V, Maioli Maria C, Filho Isaac L S, Alves Liliane R, Land Marcelo G P, Fleury Marcos K
Abstract excerpt
OBJECTIVES: Cholecystitis is one of the complications of symptomatic cholelithiasis responsible for high levels of morbidity of sickle cell disease (SCD) patients. Here, we investigated the possible protective role of single gene deletions of α-thalassaemia in the occurrence of cholelithiasis and cholecystitis in SCD patients, as well as the cholecystectomy requirements. METHODS: The α-globin genotype was...
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