Genetic Risk Factors Associated With Antiemetic Efficacy of Palonosetron, Aprepitant, and Dexamethasone in Japanese Breast Cancer Patients Treated With Anthracycline-based Chemotherapy.

doi:10.1016/j.clbc.2017.05.013

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Genetic Risk Factors Associated With Antiemetic Efficacy of Palonosetron, Aprepitant, and Dexamethasone in Japanese Breast Cancer Patients Treated With Anthracycline-based Chemotherapy.

Clinical breast cancer - 1 Apr 2018

Yokoyama Satoshi, Tamaru Satoshi, Tamaki Shinya, Nakanishi Daisuke, Mori Akiya, Yamakawa Tomokazu, Ao Takaaki, Sakata Yasuhiko, Mizuno Toshiro, Iwamoto Takuya, Watanabe Kenichi, Simomura Makoto, Kawakami Keiki, Konishi Naomi, Kageyama Shinichi, Ohtani Shoichiro, Yamada Tomomi, Ban Susumu, Ooi Kazuya

Abstract excerpt

INTRODUCTION: Breast cancer patients often receive anthracycline-based chemotherapy, and chemotherapy-induced nausea and vomiting (CINV) remains one of the most uncomfortable and distressing adverse reactions. Poor control of CINV reduces the relative dose intensity of chemotherapy agents, which has been associated with poor clinical outcomes and shorter survival. The aim of the present study was to identify...

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PMID: 28735677
DOI: 10.1016/j.clbc.2017.05.013

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ABCG2

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