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Article

Genotyping analysis of protein S-Tokushima (K196E) and the involvement of protein S antigen and activity in patients with recurrent pregnancy loss.

European journal of obstetrics, gynecology, and reproductive biology - 1 Apr 2017

Matsukawa Yasushi, Asano Eriko, Tsuda Tomohide, Kuma Hiroyuki, Kitaori Tamao, Katano Kinue, Ozaki Yasuhiko, Sugiura-Ogasawara Mayumi

Abstract excerpt

OBJECTIVE: Preston et al. indicated that Protein S (PS) deficiency was associated with stillbirths but not miscarriages. The PS-Tokushima missense variant was reported to serve as a genetic risk factor for deep vein thrombosis in the Japanese population. A previous cross-sectional study showed no increase in the prevalence of PS-Tokushima in patients with recurrent early pregnancy loss or in patients with intra...

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Identifiers

PMID: 28214760
DOI: 10.1016/j.ejogrb.2017.01.056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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