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Article

Nonsynonymous mutations in three anticoagulant genes in Japanese patients with adverse pregnancy outcomes.

Thrombosis research - 1 May 2014

Neki Reiko, Miyata Toshiyuki, Fujita Tomio, Kokame Koichi, Fujita Daisuke, Isaka Shigeyuki, Ikeda Tomoaki, Yoshimatsu Jun

Abstract excerpt

BACKGROUND: Hereditary thrombophilias may associate with uteroplacental thrombosis leading to adverse pregnancy outcomes. The present study was conducted to reveal the frequency of the low-frequency thrombophilic protein S K196E mutation, as well as the frequency of very rare nonsynonymous mutations in protein S, protein C, and antithrombin genes, in patients with adverse pregnancy outcomes. PATIENTS AND METHODS:...

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Source

Identifiers

PMID: 24613695
DOI: 10.1016/j.thromres.2014.02.012

Genes

FGR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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