Article
Genotyping analysis of the factor V Nara mutation, Hong Kong mutation, and 16 single-nucleotide polymorphisms, including the R2 haplotype, and the involvement of factor V activity in patients with recurrent miscarriage.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2017
Izuhara Mari, Shinozawa Keiko, Kitaori Tamao, Katano Kinue, Ozaki Yasuhiko, Fukutake Katsuyuki, Sugiura-Ogasawara Mayumi
Abstract excerpt
: Recurrent miscarriage can arise from a large diversity of causes and the factors responsible have not been fully clarified. The coagulation factor V R506Q (Leiden) mutation is a well known risk factor for recurrent miscarriage, although it has not been found in Japanese populations. We examined whether the factor V Nara and Hong Kong mutations, the factor V gene (F5) 16 single-nucleotide polymorphisms (SNPs),...
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