Article
The role of microRNAs in autoimmune diseases with skin involvement.
Scandinavian journal of immunology - 1 Mar 2015
Deng X, Su Y, Wu H, Wu R, Zhang P, Dai Y, Chan T-M, Zhao M, Lu Q
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively modulate gene expression by binding to the 3' untranslated region (UTR) of target messenger RNAs (mRNAs), which leads to the degradation or translational repression of their target mRNAs. Previous research on miRNAs has revealed a new paradigm of gene regulations and pathways involved in the pathogenesis of autoimmune disorders and malignant...
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