Article
Study of polymorphisms in the TP53 and RB1 genes in children with retinoblastoma in northern Mexico.
Molecular vision - 1 Jan 2017
Anaya-Pava Edwin J, Nares-Cisneros Jesús, Cárdenas-Hernández Rubén I, Jaramillo-Rodríguez Yolanda, Zambrano-Galván Graciela
Abstract excerpt
PURPOSE: To determine the frequency and association of polymorphisms in the TP53 and RB1 genes with clinical characteristics in a group of children with retinoblastoma (RB) in northern Mexico. METHODS: A prospective, longitudinal, and analytical study of 11 patients diagnosed with RB was conducted. Endpoint PCR and high-resolution real-time PCR were performed. Chi-square and Student t tests were used to evaluate...
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