Article
Spectrum of Germline Cytogenomic Alterations in RB1 in Mexican Patients With Retinoblastoma.
Pediatric blood & cancer - 1 Jun 2026
Perez-Becerra Jose de Jesus, Brukman-Jimenez Sinhue Alejandro, Ramirez-Corona Juan Antonio, Corona-Rivera Alfredo, Corona-Rivera Jorge Román, Castillo-Reyes Katia Alejandra, Gonzalez-Perez Graciela, Márquez-Mora Aurea, Serafin-Saucedo Graciela, Vera-Cuevas Violeta Cassandra, Santana-Bejarano Uriel Francisco, Orozco-Vela Mireya, Bobadilla-Morales Lucina
Abstract excerpt
OBJECTIVES: The aim of this study was to characterize the spectrum of germline cytogenomic alterations in RB1 in Mexican patients with retinoblastoma. PROCEDURES: Genomic DNA was isolated from peripheral blood from 88 Mexican patients with retinoblastoma RB (56 unilateral and 32 bilateral) treated at the Civil Hospital of Guadalajara between 2014 and 2024. Single nucleotide variants (SNVs) were analyzed by next...
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