Article
Genetic screening in Iranian patients with retinoblastoma.
Eye (London, England) - 1 Apr 2017
Shahraki K, Ahani A, Sharma P, Faranoush M, Bahoush G, Torktaz I, Gahl W A, Naseripour M, Behnam B
Abstract excerpt
PurposeThe most common intraocular tumor in childhood, retinoblastoma, is largely associated with mutations in the RB1 gene. In the most comprehensive RB1 screening in Iran, we evaluated the RB1 mutations in 106 patients with retinoblastoma, including 73 bilateral (heritable) and 33 unilateral (sporadic) cases.Patients and methodsMutations were identified using amplification refractory mutation system (ARMS) PCR...
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