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Article

The relationship between RASSF1A gene promoter methylation and the susceptibility and prognosis of melanoma: A meta-analysis and bioinformatics.

PloS one - 1 Jan 2017

Shao Chihao, Dai Wenzhu, Li Haili, Tang Wenru, Jia Shuting, Wu Xiaoming, Luo Ying

Abstract excerpt

BACKGROUND: The function of the tumor suppressor gene RASSF1A in cancer cells has been detailed in many studies. However, due to the methylation of its promoter, the expression of RASSF1A is missing in most cancers. In the literature, we found that the conclusion regarding the relationship between RASSF1A gene promoter methylation and the susceptibility and prognosis of melanoma was not unified. This study adopts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 28207831
DOI: 10.1371/journal.pone.0171676
PMCID: PMC5312935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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