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Discovery of a new family of relaxases in Firmicutes bacteria

16 Feb 2017

Abstract excerpt

Antibiotic resistance is a serious global problem. Antibiotic resistance genes (ARG), which are widespread in environmental bacteria, can be transferred to pathogenic bacteria via horizontal gene transfer (HGT). Gut microbiomes are especially apt for the emergence and dissemination of ARG. Conjugation is the HGT route that is predominantly responsible for the spread of ARG. Little is known about conjugative...

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PMID: 28207825
DOI: 10.1371/journal.pgen.1006586

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