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Article

Microcin PDI regulation and proteolytic cleavage are unique among known microcins.

Scientific reports - 16 Feb 2017

Zhao Zhe, Orfe Lisa H, Liu Jinxin, Lu Shao-Yeh, Besser Thomas E, Call Douglas R

Abstract excerpt

Microcin PDI inhibits a diversity of pathogenic Escherichia coli through the action of an effector protein, McpM. In this study we demonstrated that expression of the inhibitory phenotype is induced under low osmolarity conditions and expression is primarily controlled by the EnvZ/OmpR two-component regulatory system. Functional, mutagenesis and complementation experiments were used to empirically demonstrate...

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Identifiers

PMID: 28205647
DOI: 10.1038/srep42529
PMCID: PMC5311971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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