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Estrogen induces EGR1 to fine‐tune its actions on uterine epithelium by controlling PR signaling for successful embryo implantation

1 Nov 2017

Abstract excerpt

The harmonized actions of ovarian E 2 and progesterone (P 4 ) regulate the proliferation and differentiation of uterine cells in a spatiotemporal manner. Imbalances between these hormones often lead to infertility and gynecologic diseases. Whereas numerous factors that are involved in P 4 signaling have been identified, few local factors that mediate E2 actions in the uterus have been revealed. Here, we...

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PMID: 29092905
DOI: 10.1096/fj.201700854rr

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