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Article

Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.

Biology of reproduction - 1 Mar 2016

Waite Courtney, Mejia Rachel, Ascoli Mario

Abstract excerpt

Parturition in rodents is highly dependent on the engagement of the luteal prostaglandin F2 alpha receptor, which, through activation of the Gq/11 family of G proteins, increases the expression of Akr1c18, leading to an increase in progesterone catabolism. To further understand the involvement of Gq/11 on luteolysis and parturition, we used microarray analysis to compare the ovarian transcriptome of mice with a...

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Identifiers

PMID: 26843449
DOI: 10.1095/biolreprod.115.136952
PMCID: PMC4829089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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