Article
Low cancer prevalence in polyglutamine expansion diseases.
Neurology - 21 Mar 2017
Coarelli Giulia, Diallo Alhassane, Thion Morgane Sonia, Rinaldi Daisy, Calvas Fabienne, Boukbiza Ouahid Lagha, Tataru Alina, Charles Perrine, Tranchant Christine, Marelli Cecilia, Ewenczyk Claire, Tchikviladzé Maya, Monin Marie-Lorraine, Carlander Bertrand, Anheim Mathieu, Brice Alexis, Mochel Fanny, Tezenas du Montcel Sophie, Humbert Sandrine, Durr Alexandra
Abstract excerpt
OBJECTIVE: Polyglutamine (PolyQ) diseases are dominantly transmitted neurologic disorders, caused by coding and expanded CAG trinucleotide repeats. Cancer was reported retrospectively to be rare in patients with PolyQ diseases and we aimed to investigate its prevalence in France. METHODS: Consecutive patients with Huntington disease (HD) and spinocerebellar ataxia (SCA) were questioned about cancer,...
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