Article
An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo
15 Feb 2017
Abstract excerpt
BACKGROUND: Aging human skin undergoes significant morphological and functional changes such as wrinkle formation, reduced wound healing capacity, and altered epidermal barrier function. Besides known age-related alterations like DNA-methylation changes, metabolic adaptations have been recently linked to impaired skin function in elder humans. Understanding of these metabolic adaptations in aged skin is of...
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