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Article

The influence of the tumor necrosis factor-alpa-308G>A polymorphism on the efficacy of immunosuppressive therapy in patients after kidney transplantation.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society - 1 Dec 2016

M Kotowski M, Bogacz A, Bartkowiak-Wieczorek J, Sienko J, Procyk D, Dziewanowski K, Ostrowski M, Czerny B, Grzeskowiak E, Machalinski B

Abstract excerpt

Cytokines play an important role in the immune response. The calcineurin inhibitors (cyclosporine CsA, tacrolimus TAC) widely used after renal transplantation to prevent allograft rejection are immunosuppressive drugs suppressing the production of cytokines. These drugs are characterized by interindividual variability and require monitoring their blood concentrations to predict their optimal dosage. Therefore,...

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PMID: 28195062

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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