Article
Does MMP-9 Gene Polymorphism Play a Role in Pituitary Adenoma Development?
Disease markers - 1 Jan 2017
Glebauskiene Brigita, Liutkeviciene Rasa, Vilkeviciute Alvita, Kriauciuniene Loresa, Jakstiene Silvija, Zlatkute Egle, Tamosiunas Abdonas, Zemaitiene Reda, Vaitkiene Paulina, Zaliuniene Dalia
Abstract excerpt
Purpose. To determine if the MMP-9 genotype has an influence on development of pituitary adenoma (PA). Methodology. The study enrolled n = 86 patients with PA and n = 526 healthy controls (reference group). The genotyping of MMP-9 was carried out using the real-time polymerase chain reaction method. Results. Our data demonstrated that the MMP-9 (-1562) C/C genotype was more frequent in PA group than in healthy...
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