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Article

N-myc downstream-regulated gene 2 (NDRG2) promoter methylation and expression in pituitary adenoma.

Diagnostic pathology - 8 Apr 2017

Vaitkiene Paulina, Valiulyte Indre, Glebauskiene Brigita, Liutkeviciene Rasa

Abstract excerpt

BACKGROUND: Pituitary adenoma (PA) is a benign primary tumor that arises from the pituitary gland and is associated with ophthalmological, neurological and endocrinological abnormalities. However, causes that increase tumor progressing recurrence and invasiveness are still undetermined. Several studies have shown N-myc downstream regulated gene 2 (NDRG2) as a tumor suppressor gene, but the role of NDRG2 gene in...

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Share to Acromegaly
Share to Adenoma
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Heterogeneity

Share to Pituitary Neoplasms

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28390436
DOI: 10.1186/s13000-017-0622-7
PMCID: PMC5385074

Genes

NDRG2
PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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