Article
Variant call concordance between two laboratory-developed, solid tumor targeted genomic profiling assays using distinct workflows and sequencing instruments.
Experimental and molecular pathology - 1 Apr 2017
Hampel Ken J, de Abreu Francine B, Sidiropoulos Nikoletta, Peterson Jason D, Tsongalis Gregory J
Abstract excerpt
Targeted genomic profiling (TGP) using massively parallel DNA sequencing is becoming the standard methodology in clinical laboratories for detecting somatic variants in solid tumors. The variety of methodologies and sequencing platforms in the marketplace for TGP has resulted in a variety of clinical TGP laboratory developed tests (LDT). The variability of LDTs is a challenge for test-to-test and...
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