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Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells.

Stem cells (Dayton, Ohio) - 1 Oct 2009

Buchholz David E, Hikita Sherry T, Rowland Teisha J, Friedrich Amy M, Hinman Cassidy R, Johnson Lincoln V, Clegg Dennis O

Abstract excerpt

Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem cells (hESCs) to differentiate into specialized cell types. Ocular cells such as the retinal pigmented epithelium (RPE) are of particular interest because they could be used to treat degenerative eye diseases, including age-related macular degeneration and...

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Source

Identifiers

PMID: 19658190
DOI: 10.1002/stem.189

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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