Article
Serum iron level and kidney function: a Mendelian randomization study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Feb 2017
Del Greco M Fabiola, Foco Luisa, Pichler Irene, Eller Philipp, Eller Kathrin, Benyamin Beben, Whitfield John B, Pramstaller Peter P, Thompson John R, Pattaro Cristian, Minelli Cosetta
Abstract excerpt
Background: Iron depletion is a known consequence of chronic kidney disease (CKD), but there is contradicting epidemiological evidence on whether iron itself affects kidney function and whether its effect is protective or detrimental in the general population. While epidemiological studies tend to be affected by confounding and reverse causation, Mendelian randomization (MR) can provide unconfounded estimates of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.