Article
Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes.
Diabetes care - 1 Apr 2017
Shah Ravi, Murthy Venkatesh, Pacold Michael, Danielson Kirsty, Tanriverdi Kahraman, Larson Martin G, Hanspers Kristina, Pico Alexander, Mick Eric, Reis Jared, de Ferranti Sarah, Freinkman Elizaveta, Levy Daniel, Hoffmann Udo, Osganian Stavroula, Das Saumya, Freedman Jane E
Abstract excerpt
OBJECTIVE: Insulin resistance (IR) is a hallmark of obesity and metabolic disease. Circulating extracellular RNAs (ex-RNAs), stable RNA molecules in plasma, may play a role in IR, though most studies on ex-RNAs in IR are small. We sought to characterize the relationship between ex-RNAs and metabolic phenotypes in a large community-based human cohort. RESEARCH DESIGN AND METHODS: We measured circulating plasma...
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