Article
Frequency of Epidermal Growth Factor Receptor Mutation in Smokers with Lung Cancer Without Pulmonary Emphysema.
Anticancer research - 1 Feb 2017
Takeda Kenichi, Yamasaki Akira, Igishi Tadashi, Kawasaki Yuji, Ito-Nishii Shizuka, Izumi Hiroki, Sakamoto Tomohiro, Touge Hirokazu, Kodani Masahiro, Makino Haruhiko, Yanai Masaaki, Tanaka Natsumi, Matsumoto Shingo, Araki Kunio, Nakamura Hiroshige, Shimizu Eiji
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease is a smoking-related disease, and is categorized into the emphysema and airway dominant phenotypes. We examined the relationship between emphysematous changes and epidermal growth factor receptor (EGFR) mutation status in patients with lung adenocarcinoma. PATIENTS AND METHODS: The medical records for 250 patients with lung adenocarcinoma were retrospectively...
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