Article
Systematic Profiling of Short Tandem Repeats in the Cattle Genome.
Genome biology and evolution - 1 Jan 2017
Xu Lingyang, Haasl Ryan J, Sun Jiajie, Zhou Yang, Bickhart Derek M, Li Junya, Song Jiuzhou, Sonstegard Tad S, Van Tassell Curtis P, Lewin Harris A, Liu George E
Abstract excerpt
Short tandem repeats (STRs), or microsatellites, are genetic variants with repetitive 2–6 base pair motifs in many mammalian genomes. Using high-throughput sequencing and experimental validations, we systematically profiled STRs in five Holsteins. We identified a total of 60,106 microsatellites and generated the first high-resolution STR map, representing a substantial pool of polymorphism in dairy cattle. We...
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