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The genomic landscape of short tandem repeats in cattle.

Animal genetics - 1 Feb 2025

Wang Pengfei, Sheng Xin, Xia Xiaoting, Wang Fuwen, Li Ruizhe, Ahmed Zulfiqar, Chen Ningbo, Lei Chuzhao, Ma Zhijie

Abstract excerpt

Short tandem repeats (STRs) are abundant and have high mutation rates across cattle genomes; however, comprehensive exploration of cattle STRs is needed. Here, we constructed a comprehensive map of 467 553 polymorphic STRs (pSTRs) constructed from 423 cattle genomes representing 59 breeds worldwide. We observed that pSTRs in coding sequences and 5'UTRs (Untranslated Regions) were under strong selective...

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PMID: 39692037
DOI: 10.1111/age.13498

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