Article
Whole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle.
Proceedings of the National Academy of Sciences of the United States of America - 15 May 2012
Larkin Denis M, Daetwyler Hans D, Hernandez Alvaro G, Wright Chris L, Hetrick Lorie A, Boucek Lisa, Bachman Sharon L, Band Mark R, Akraiko Tatsiana V, Cohen-Zinder Miri, Thimmapuram Jyothi, Macleod Iona M, Harkins Timothy T, McCague Jennifer E, Goddard Michael E, Hayes Ben J, Lewin Harris A
Abstract excerpt
Using a combination of whole-genome resequencing and high-density genotyping arrays, genome-wide haplotypes were reconstructed for two of the most important bulls in the history of the dairy cattle industry, Pawnee Farm Arlinda Chief ("Chief") and his son Walkway Chief Mark ("Mark"), each accounting for ∼7% of all current genomes. We aligned 20.5 Gbp (∼7.3× coverage) and 37.9 Gbp (∼13.5× coverage) of the Chief...
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