Article
Developing a new nonbinary SNP fluorescent multiplex detection system for forensic application in China.
Electrophoresis - 1 Apr 2017
Liu Yanfang, Liao Huidan, Liu Ying, Guo Juanjuan, Sun Yi, Fu Xiaoliang, Xiao Ding, Cai Jifeng, Lan Lingmei, Xie Pingli, Zha Lagabaiyila
Abstract excerpt
Nonbinary single-nucleotide polymorphisms (SNPs) are potential forensic genetic markers because their discrimination power is greater than that of normal binary SNPs, and that they can detect highly degraded samples. We previously developed a nonbinary SNP multiplex typing assay. In this study, we selected additional 20 nonbinary SNPs from the NCBI SNP database and verified them through pyrosequencing. These 20...
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