Article
Establishment of a Novel Myelodysplastic Syndrome (MDS) Xenotransplantation Model.
Clinical laboratory - 1 Sept 2016
Ma Ling, Zhang Xia, Wang Zhiqiong, Chen Yan, Wei Jia, Hu Lihua
Abstract excerpt
BACKGROUND: Myelodysplastic syndrome (MDS) is a clonal disease of the elderly characterized by chronic cytopenia, dysplasia, and a high risk of progression to acute myeloid leukemia (AML). Up until now, few animal models that fully recapitulate clinical features of this disease have been available. METHODS: This study aimed to establish a new MDS xenograft model utilizing a human MDS-derived cell line with...
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