Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-10 expression in macrophages from neonates born from obese mothers is suppressed by IL-4 and LPS/INFγ.

Journal of cellular physiology - 1 Dec 2017

Cifuentes-Zúñiga Francisca, Arroyo-Jousse Viviana, Soto-Carrasco Gustavo, Casanello Paola, Uauy Ricardo, Krause Bernardo J, Castro-Rodríguez José A

Abstract excerpt

Obese women offspring have a higher risk of developing chronic diseases associated with an altered immune function. We aim to determine, in neonatal monocyte-derived macrophages, whether maternal obesity is associated with an altered expression and DNA methylation of pro- and anti-inflammatory genes, along with a higher pro-inflammatory response. Cord blood from newborns of obese (Ob) and lean (control) women...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to Fetal Blood

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation Mediators

Share to Interleukin-10

Share to Interleukin-4

Share to Leptin

Share to Lipopolysaccharides

Share to Maternal Nutritional Physiological Phenomena

Source

Identifiers

PMID: 28160500
DOI: 10.1002/jcp.25845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-10 expression in macrophages from neonates born from obese mothers is suppressed by IL-4 and LPS/INFγ.PMID 28160500Read ↗

Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?Semantic proximity Read ↗

Adverse effects of gestational diabetes mellitus on fetal monocytes revealed by single-cell RNA sequencingSemantic proximity Read ↗

Distinct role of FoxO1 in M-CSF- and GM-CSF-differentiated macrophages contributes LPS-mediated IL-10: implication in hyperglycemiaSemantic proximity Read ↗

Macrophages at the Fetal–Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10Semantic proximity Read ↗

The effect of maternal Inflammation on foetal programming of metabolic diseaseSemantic proximity Read ↗

Human adipose tissue macrophages are enhanced but changed to an anti-inflammatory profile in obesity.Semantic proximity Read ↗

MicroRNAs of the miR-17~92 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expressionSemantic proximity Read ↗

Maternal obesity is associated with phenotypic alterations in fetal immune cells by single-cell mass cytometry.Semantic proximity Read ↗

Epigenetic and Molecular Alterations in Obesity: Linking CRP and DNA Methylation to Systemic InflammationSemantic proximity Read ↗

Epigenetic Mechanisms in Monocytes/Macrophages Regulate Inflammation in Cardiometabolic and Vascular DiseaseSemantic proximity Read ↗

Phenotypic Switch of Adipose Tissue Macrophages as a Target to Reduce Obesity-Associated Metabolic RiskSemantic proximity Read ↗

Obesity in Humans Is Characterized by Gut Inflammation as Shown by Pro-Inflammatory Intestinal Macrophage Accumulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.