Sinusoidal obstruction syndrome following CD33-targeted therapy in acute myeloid leukemia

Abstract excerpt

To the editor: In late December 2016, Seattle Genetics, Inc., announced that the US Food and Drug Administration (FDA) had placed a hold or partial hold on several early-stage clinical trials of vadastuximab talirine (SGN-CD33A) in acute myeloid leukemia (AML) to further evaluate the potential risk

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