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Article

Impact of HOTAIR Gene Polymorphism and Environmental Risk on Oral Cancer.

Journal of dental research - 1 Jun 2018

Su S C, Hsieh M J, Lin C W, Chuang C Y, Liu Y F, Yeh C M, Yang S F

Abstract excerpt

Genetic and acquired factors are thought to be interrelated and imperative to estimate the risk and prognosis of oral squamous cell carcinoma (OSCC). HOX transcript antisense intergenic RNA ( HOTAIR) plays crucial roles in gene regulation and is regulated in a variety of cancers. Polymorphisms in HOTAIR have been recently linked to the predisposition to diverse malignancies. In the present study, we aimed to...

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PMID: 29298397
DOI: 10.1177/0022034517749451

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