Article
IutB participates in the ferric-vulnibactin utilization system in Vibrio vulnificus M2799.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine - 1 Apr 2017
Kawano Hiroaki, Miyamoto Katsushiro, Negoro Miho, Zushi Eriko, Tsuchiya Takahiro, Tanabe Tomotaka, Funahashi Tatsuya, Tsujibo Hiroshi
Abstract excerpt
Vibrio vulnificus, an opportunistic pathogen that causes a serious, often fatal, infection in humans, requires iron for its growth. This bacterium utilizes iron from the environment via the vulnibactin-mediated iron uptake system. The mechanisms of vulnibactin biosynthesis, vulnibactin export, and ferric-vulnibactin uptake systems have been reported, whereas the ferric-vulnibactin reduction mechanism in the cell...
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