Article
Effect of the crp mutation on the utilization of transferrin-bound iron by Vibrio vulnificus.
FEMS microbiology letters - 1 Apr 2006
Choi Mi-Hwa, Sun Hui-Yu, Park Ra-Young, Kim Choon-Mee, Bai Young-Hoon, Kim Young-Ran, Rhee Joon-Haeng, Shin Sung-Heui
Abstract excerpt
Cyclic AMP-cAMP receptor protein (CRP) complex plays an essential role in the global regulation of Vibrio vulnificus virulence. We found that growth retardation of V. vulnificus caused by mutation of the crp gene encoding CRP was exacerbated under iron-limited conditions. Accordingly, we investigated the effect of crp mutation on the expression of the vulnibactin-mediated iron-uptake system and the ability of V....
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